Featuring 10 symposium papers presented in Indianapolis, IN in June 2013. These papers have a rich history having evolved from five decades of tradition, from a symposium that has provided an international forum for the presentation of current research results, applications studies, and open discussion. Papers on radiation effects in reactor pressure vessel steels dominated The Effects of Radiation on Nuclear Materials symposium. More than half of the contributions to these papers are from international, expert authors. While a long-standing topic of research and practical interest to the nuclear engineering community, this topic retains its currency due the irreplaceability of the vessel and the critical role vessel safety calculations play in establishing the licensable life of the plant.